Which process has an open handle on my file x (fuser, lsof or Process Explorer)?

Here’s how to find out if a file is locked because of another process that still has an open file handle.

On Linux/Unix just use: fuser or lsof

lsof | grep
fuser -v

On Windows the Sysinternals Process Explorer is a great answer to this (and many other questions):

Just Ctrl+F and enter the name or part of it and search